L-alpha-glycerophosphoryl choline

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  • Name: L-alpha-glycerophosphoryl choline
  • Description: Choline alfoscerate is a member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells. It has a role as a... parasympatholytic, a neuroprotective agent, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a member of sn-glycerol 3-phosphates and a member of phosphocholines. (CHEBI:16870)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
18384253 Age 24.5 ± 3, Gender ⚥ 0.7 (mean value of the compound area) LC-MS; GC-MS plasma
18384253 Age 40.8 ± 5.6, Gender ⚥ 0.93 (mean value of the compound area) LC-MS; GC-MS plasma
18384253 Age 55.6 ± 3.7, Gender ⚥ 0.97 (mean value of the compound area) LC-MS; GC-MS plasma
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    choline alfoscerate;alpha-GPC
  • Chemical Formula:
    C8H20NO6P
  • Exact Mass g/mol:
    257.1030000
  • Systematic name:
    [(2R)-2,3-dihydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
  • SMILES:
    C[N+](C)(C)CCOP(=O)([O-])OC[C@@H](CO)O
  • InChI:
    [(2R)-2,3-dihydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
  • InChI Key:
    SUHOQUVVVLNYQR-MRVPVSSYSA-N
  • CAS number:
    28319-77-9
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Extracellular, Human body biofluids, Biofluid tissues, Blood, Plasma, Cerebrospinal fluid, Breast milk, Seminal fluid, Organ, Brain, Kidney, Prostate, Spleen, Tissue, Cellular (general class), Subcellular, Cell membrane, Cytoplasm, Excreta material, Feces
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: LC-MS; GC-MS
Sample: plasma
PubMed PMID: 18384253