2-hydroxyisobutyrate

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  • Name: 2-hydroxyisobutyrate
  • Description: A hydroxy fatty acid anion that is the conjugate base of 2-hydroxyisobutyric acid, arising from deprotonation of the carboxyl group. It is the major species at pH 7.3. (CHEBI:19641)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
23838602 Age [17–85], Gender ⚥ 0.017 (β) UHPLC/MS/MS serum + plasma
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    α-hydroxy-α-methylpropionate; α-hydroxyisobutanoate; alpha-hydroxyisobutyrate; 2-methyllactate; alpha-hydroxyisobutanoate; α-hydroxyisobutyrate;alpha-hydroxy-alpha-methylpropanoate
  • Chemical Formula:
    C4H7O3-
  • Exact Mass g/mol:
    103.0400000
  • Systematic name:
    2-hydroxy-2-methylpropanoate
  • SMILES:
    CC(C)(C(=O)[O-])O
  • InChI:
    InChI=1S/C4H8O3/c1-4(2,7)3(5)6/h7H,1-2H3,(H,5,6)/p-1
  • InChI Key:
    BWLBGMIXKSTLSX-UHFFFAOYSA-M
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Tissue
  • Metabolite source:
    Homo sapiens, exogenous metabolite
Age-variations
Linear regression
Method: UHPLC/MS/MS
Sample: serum + plasma
PubMed PMID: 23838602
β = 0.017 (y = βx + α)
p-value < 0.05
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