alpha-hydroxyisovalerate

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  • Name: alpha-hydroxyisovalerate
  • Description: A hydroxy monocarboxylic acid anion that is the conjugate base of 2-hydroxy-3-methylbutyric acid, formed by loss of a proton from the carboxyl group. It has a role as a human metabolite. (CHEBI:64669)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
23838602 Age [17–85], Gender ⚥ -0.008 (β) UHPLC/MS/MS serum + plasma
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    DL-2-Hydroxyisovalerate;2-Hydroxy-3-methylbutyrate; DL-2-Hydroxy-3-methylbutanoate; 2-Hydroxyisopentanoate; 2-Hydroxyisovalerate; DL-alpha-hydroxyisovalerate
  • Chemical Formula:
    C5H9O3-
  • Exact Mass g/mol:
    117.0550000
  • Systematic name:
    2-hydroxy-3-methylbutanoate
  • SMILES:
    CC(C)C(C(=O)[O-])O
  • InChI:
    InChI=1S/C5H10O3/c1-3(2)4(6)5(7)8/h3-4,6H,1-2H3,(H,7,8)/p-1
  • InChI Key:
    NGEWQZIDQIYUNV-UHFFFAOYSA-M
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Serum, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Linear regression
Method: UHPLC/MS/MS
Sample: serum + plasma
PubMed PMID: 23838602
β = -0.008 (y = βx + α)
p-value < 0.05