malate

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  • Name: malate
  • Description: A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of malic acid.. (CHEBI:25115)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
27374292 Age [25–35] (median=32), Gender ♂ (Japanese) 0.980079 (average level of metabolite) UHPLC-MS/MS Negative mode serum
27374292 Age [55–64] (median=60), Gender ♂ (Japanese) 1.21585 (average level of metabolite) UHPLC-MS/MS Negative mode serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
23838602 Age [17–85], Gender ⚥ 0.013 (β) UPLC-MS/MS; GC-MS serum, plasma
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    malic acid anion;malate anion
  • Chemical Formula:
    C4H4O5-2
  • Exact Mass g/mol:
    132.0060000
  • Systematic name:
    2-hydroxybutanedioate
  • SMILES:
    C(C(C(=O)[O-])O)C(=O)[O-]
  • InChI:
    InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/p-2
  • InChI Key:
    BJEPYKJPYRNKOW-UHFFFAOYSA-L
  • CAS number:
    149-61-1
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Serum, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: UHPLC-MS/MS Negative mode
Sample: serum
PubMed PMID: 27374292
Linear regression
Method: UPLC-MS/MS; GC-MS
Sample: serum; plasma
PubMed PMID: 23838602
β = 0.013 (y = βx + α)
p-value < 0.05
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