3-dehydrocarnitine

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  • Name: 3-dehydrocarnitine
  • Description: 3-Dehydrocarnitine is a member of the carnitine family that is an intermediate in carnitine degradation. It can be formed from either D-carnitine or L-carnitine and the enzyme responsible for this ... oxidation reaction is (S)-carnitine 3-dehydrogenase (EC 1. 1. 1. 254) or carnitine 3-dehydrogenase (EC 1. 1. 1. 108), respectively. Carnitine is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine. In living cells, it is required for the transport of fatty acids from the cytosol into the mitochondria during the breakdown of lipids (or fats) for the generation of metabolic energy. (HMDB0012154)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
23838602 Age [17–85], Gender ⚥ 0.015 (β) UPLC-MS/MS; GC-MS serum, plasma
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Chemical Formula:
    C7H13NO3
  • Exact Mass g/mol:
    159.0900000
  • Systematic name:
    3-oxo-4-(trimethylazaniumyl)butanoate
  • SMILES:
    C[N+](C)(C)CC(=O)CC(=O)[O-]
  • InChI:
    InChI=1S/C7H13NO3/c1-8(2,3)5-6(9)4-7(10)11/h4-5H2,1-3H3
  • InChI Key:
    YNOWULSFLVIUDH-UHFFFAOYSA-N
  • CAS number:
    10457-99-5
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Serum, Saliva, Urine, Tissue, Excreta material, Feces
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Linear regression
Method: UPLC-MS/MS; GC-MS
Sample: serum; plasma
PubMed PMID: 23838602
β = 0.015 (y = βx + α)
p-value < 0.05
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