acetylcarnitine
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Name: acetylcarnitine
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Description: O-acetylcarnitine is an O-acylcarnitine having acetyl as the acyl substituent. It has a role as a human metabolite. It derives from an acetic acid. It is a conjugate base of an O-acetylcarnitinium....
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 30113646 | Age 44.6 ± 14, Gender ♀ (Dutch) | 5.7 (μmol/L) | ESI-MS/MS | plasma |
| 30113646 | Age 44.6 ± 13, Gender ♀ (South-Asian Surinamese) | 5.6 (μmol/L) | ESI-MS/MS | plasma |
| 30113646 | Age 44.6 ± 14, Gender ♀ (Dutch) | 107.0 (% (percentage of metabolite concentration compared with baseline (100%) per 10 year increment in age; analyses were adjusted for BMI)) | ESI-MS/MS | plasma |
| 30113646 | Age 44.6 ± 13, Gender ♀ (South-Asian Surinamese) | 105.2 (% (percentage of metabolite concentration compared with baseline (100%) per 10 year increment in age; analyses were adjusted for BMI)) | ESI-MS/MS | plasma |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 23838602 | Age [17–85], Gender ⚥ | 0.017 (β) | UPLC-MS/MS; GC-MS | serum, plasma |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Synonym:O-acetylcarnitine
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Chemical Formula:C9H17NO4
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Exact Mass g/mol:203.1160000
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Systematic name:3-acetyloxy-4-(trimethylazaniumyl)butanoate
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SMILES:CC(=O)OC(CC(=O)[O-])C[N+](C)(C)C
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InChI:InChI=1S/C9H17NO4/c1-7(11)14-8(5-9(12)13)6-10(2,3)4/h8H,5-6H2,1-4H3
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InChI Key:RDHQFKQIGNGIED-UHFFFAOYSA-N
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CAS number:870-77-9; 14992-62-2
Related resources
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Literature sources:
- Menni C et al., Metabolomic markers reveal novel pathways of ageing and early development in human populations., International journal of epidemiology, 1111-9, 2013
- Muilwijk M et al., The Association of Acylcarnitines and Amino Acids With Age in Dutch and South-Asian Surinamese Living in Amsterdam., The Journal of clinical endocrinology and metabolism, 3783-3791, 2018
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External links:
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Serum, Tissue
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Metabolite source:Homo sapiens, endogenous metabolite
Age-variations
Linear regression
Method: UPLC-MS/MS; GC-MS
Sample: serum; plasma
β = 0.017
(y = βx + α)
p-value < 0.05