alpha-hydroxyisocaproate

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  • Name: alpha-hydroxyisocaproate
  • Description: Alpha-hydroxyisocaproate is a 2-hydroxy fatty acid anion that is the conjugate base of 2-hydroxy-4-methylvaleric acid, obtained by deprotonation of the carboxyl group. It is the major species at pH... 7.3. It has a role as a metabolite. It is a methyl-branched fatty acid anion. It derives from a valeric acid. (CHEBI:133577)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
27374292 Age [25–35] (median=32), Gender ♀ (Japanese) 1.030526 (average level of metabolite) UHPLC-MS/MS Negative mode serum
27374292 Age [55–65] (median=60), Gender ♀ (Japanese) 0.810998 (average level of metabolite) UHPLC-MS/MS Negative mode serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    2-hydroxy-4-methylvalerate; alpha-hydroxy-gamma-methylpentanoate; alpha-hydroxyisohexanoate; DL-2-hydroxy-4-methylvalerate; alpha-hydroxy-4-methylpentanoate; 2-hydroxyisocaproate; 2-hydroxyisohexanoate; DL-leucate
  • Chemical Formula:
    C6H11O3-
  • Systematic name:
    2-hydroxy-4-methylpentanoate
  • SMILES:
    CC(C)CC(C(=O)[O-])O
  • InChI:
    InChI=1S/C6H12O3/c1-4(2)3-5(7)6(8)9/h4-5,7H,3H2,1-2H3,(H,8,9)/p-1
  • InChI Key:
    LVRFTAZAXQPQHI-UHFFFAOYSA-M
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: UHPLC-MS/MS Negative mode
Sample: serum
PubMed PMID: 27374292
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