ophthalmic acid
-
Name: ophthalmic acid
-
Description: Ophthalmic acid, also known as ophthalmate (chemically L-γ-glutamyl-L-α-aminobutyrylglycine), is a tripeptide analog of glutathione in which the cysteine group is replaced by L-2-aminobutyrate. It ...
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 27036001 | Age 29 ± 4, Gender ⚥ | 0.42 (CV (CV=SD of metabolite abundance (peak areas from LC-MS) divided by the mean)) | LC-MS | blood |
| 27036001 | Age 81 ± 7, Gender ⚥ | 0.24 (CV (CV=SD of metabolite abundance (peak areas from LC-MS) divided by the mean)) | LC-MS | blood |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
-
Synonym:gamma-Glu-alpha-aminobutyryl-Gly
-
Chemical Formula:C11H19N3O6
-
Exact Mass g/mol:289.1270000
-
Systematic name:(2S)-2-amino-5-[[(2S)-1-(carboxymethylamino)-1-oxobutan-2-yl]amino]-5-oxopentanoic acid; N-{(2S)-1-[(carboxymethyl)amino]-1-oxobutan-2-yl}-L-glutamine;(2S)-2-amino-4-{[(1S)-1-[(carboxymethyl)carbamoyl]propyl]carbamoyl}butanoic acid
-
SMILES:CCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N
-
InChI:InChI=1S/C11H19N3O6/c1-2-7(10(18)13-5-9(16)17)14-8(15)4-3-6(12)11(19)20/h6-7H,2-5,12H2,1H3,(H,13,18)(H,14,15)(H,16,17)(H,19,20)/t6-,7-/m0/s1
-
InChI Key:JCMUOFQHZLPHQP-BQBZGAKWSA-N
-
CAS number:495-27-2
Related resources
-
Literature sources:
- Chaleckis R et al., Individual variability in human blood metabolites identifies age-related differences., Proceedings of the National Academy of Sciences of the United States of America, 4252-9, 2016
Metabolite sources and localization
-
Metabolite location:Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Tissue
-
Metabolite source:Homo sapiens, endogenous metabolite