gamma-glutamylphenylalanine

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  • Name: gamma-glutamylphenylalanine
  • Description: Gamma-Glutamylphenylalanine is a dipeptide composed of gamma-glutamate and phenylalanine, and is a proteolytic breakdown product of larger proteins. It is probably formed by transpeptidation betwee... n glutathione and the corresponding amino acid, catalyzed by gamma-glutamyl transpeptidase (PMID: 237763)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
27374292 Age [25–35] (median=32), Gender ♀ (Japanese) 0.801076 (average level of metabolite) UHPLC-MS/MS Positive mode serum
27374292 Age [55–65] (median=60), Gender ♀ (Japanese) 0.940495 (average level of metabolite) UHPLC-MS/MS Positive mode serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    γ-Glu-Phe; gamma-Glu-Phe; N-L-gamma-glutamyl-3-phenyl-L-alanine; N-L-gamma-glutamyl-L-phenylalanine;gamma-L-Glu-L-Phe
  • Chemical Formula:
    C14H18N2O5
  • Systematic name:
    (2S)-2-amino-5-[[(1S)-1-carboxy-2-phenylethyl]amino]-5-oxopentanoic acid
  • SMILES:
    C1=CC=C(C=C1)CC(C(=O)O)NC(=O)CCC(C(=O)O)N
  • InChI:
    InChI=1S/C14H18N2O5/c15-10(13(18)19)6-7-12(17)16-11(14(20)21)8-9-4-2-1-3-5-9/h1-5,10-11H,6-8,15H2,(H,16,17)(H,18,19)(H,20,21)/t10-,11-/m0/s1
  • InChI Key:
    XHHOHZPNYFQJKL-QWRGUYRKSA-N
  • CAS number:
    7432-24-8
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Urine, Organ, Kidney, Tissue, Cellular (general class), Subcellular, Cytoplasm, Excreta material, Feces
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: UHPLC-MS/MS Positive mode
Sample: serum
PubMed PMID: 27374292