isoleucylglycine

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  • Name: isoleucylglycine
  • Description: Isoleucyl-Glycine is a dipeptide composed of isoleucine and glycine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiologica... l or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis (HMDB0028907).
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
27374292 Age [25–35] (median=32), Gender ♀ (Japanese) 0.815887 (average level of metabolite) UHPLC-MS/MS Positive mode serum
27374292 Age [55–65] (median=60), Gender ♀ (Japanese) 1.248513 (average level of metabolite) UHPLC-MS/MS Positive mode serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    DL-Ile-Gly; IG dipeptide; 2-[(2-amino-3-methylpentanoyl)amino]ethanoic acid; 2-(2-amino-3-methylpentanamido)acetic acid
  • Chemical Formula:
    C8H16N2O3
  • Systematic name:
    2-[(2-amino-3-methylpentanoyl)amino]acetic acid
  • SMILES:
    CCC(C)C(C(=O)NCC(=O)O)N
  • InChI:
    InChI=1S/C8H16N2O3/c1-3-5(2)7(9)8(13)10-4-6(11)12/h5,7H,3-4,9H2,1-2H3,(H,10,13)(H,11,12)
  • InChI Key:
    UCGDDTHMMVWVMV-UHFFFAOYSA-N
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Tissue, Excreta material, Feces
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: UHPLC-MS/MS Positive mode
Sample: serum
PubMed PMID: 27374292
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