12-HETE
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Name: 12-HETE
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Description: A HETE that is icosa-5,8,10,14-tetraenoic acid substituted by a hydroxy group at position 12. It is a metabolite of arachidonic acid. (CHEBI:19138)
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 27374292 | Age [25–35] (median=32), Gender ♀ | 0.695622 (mean value of the compound area) | LC/MS Neg | serum |
| 27374292 | Age [55-65] (median=60), Gender ♀ | 1.910123 (mean value of the compound area) | LC/MS Neg | serum |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Chemical Formula:C20H32O3
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Systematic name:(5Z,8Z,10E,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoic acid
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SMILES:CCCCCC=CCC(C=CC=CCC=CCCCC(=O)O)O
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InChI:InChI=1S/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7-,11-8-,13-10-,17-14+
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InChI Key:ZNHVWPKMFKADKW-VXBMJZGYSA-N
Related resources
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Literature sources:
- Saito K et al., Gender- and Age-Associated Differences in Serum Metabolite Profiles among Japanese Populations., Biological & pharmaceutical bulletin, 1179-86, 2016
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External links:
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Extracellular, Human body biofluids, Biofluid tissues, Blood, Serum, Cerebrospinal fluid, Saliva, Urine, Tissue, Excreta material
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Metabolite source:Homo sapiens, endogenous metabolite