2-monoolein

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  • Name: 2-monoolein
  • Description: 2-Oleoylglycerol (2OG) is a monoacylglycerol that is found in biologic tissues. Its synthesis is derived from diacylglycerol precursors. It is metabolized to oleic acidand glycerol primarily by the... enzyme monoacylglycerol lipase (MAGL). In 2011, 2OG was found to be an endogenous ligand to GPR119. 2OG has been shown to increase glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) levels following administration to the small intestine. (https://en.wikipedia.org/wiki/2-Oleoylglycerol)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
27374292 Age [25–35] (median=32), Gender ♂ 0.907985 (mean value of the compound area) LC/MS Neg serum
27374292 Age [55-64] (median=60), Gender ♂ 1.834331 (mean value of the compound area) LC/MS Neg serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    2-mono-C18:1;MG (0:0/18:1/0:0)
  • Chemical Formula:
    C21H40O4
  • Systematic name:
    1,3-dihydroxypropan-2-yl (Z)-octadec-9-enoate
  • SMILES:
    CCCCCCCCC=CCCCCCCCC(=O)OC(CO)CO
  • InChI:
    InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
  • InChI Key:
    UPWGQKDVAURUGE-KTKRTIGZSA-N
  • CAS number:
    3443-84-3
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: LC/MS Neg
Sample: serum
PubMed PMID: 27374292
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