leucine
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Name: leucine
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Description: An unspecified stereoisomerism form of leucine. One of nine essential amino acids in humans (provided by food), Leucine is important for protein synthesis and many metabolic functions. Leucine cont...
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 27036001 | Age 29 ± 4, Gender ⚥ | 0.26 (CV (CV=SD of metabolite abundance (peak areas from LC-MS) divided by the mean)) | LC-MS | red blood cells, plasma, blood |
| 27036001 | Age 81 ± 7, Gender ⚥ | 0.27 (CV (CV=SD of metabolite abundance (peak areas from LC-MS) divided by the mean)) | LC-MS | red blood cells, plasma, blood |
| 18384253 | Age 24.5 ± 3, Gender ⚥ | 0.71 (mean value of the compound area) | LC-MS; GC-MS | plasma |
| 18384253 | Age 40.8 ± 5.6, Gender ⚥ | 1.07 (mean value of the compound area) | LC-MS; GC-MS | plasma |
| 18384253 | Age 55.6 ± 3.7, Gender ⚥ | 1.4 (mean value of the compound area) | LC-MS; GC-MS | plasma |
| 12768504 | Age 32.6 ± 4.4 , Gender ♀ | 117.0 (μmol/l) | LC | blood |
| 12768504 | Age 48 ± 4.3, Gender ♀ | 121.0 (μmol/l) | LC | blood |
| 12768504 | Age 74.7 ± 10, Gender ♀ | 103.0 (μmol/l) | LC | blood |
| 12768504 | Age 33.3 ± 3.8, Gender ♂ | 166.0 (μmol/l) | LC | blood |
| 12768504 | Age 48.4 ± 6, Gender ♂ | 151.0 (μmol/l) | LC | blood |
| 12768504 | Age 75.9 ± 9.3, Gender ♂ | 130.0 (μmol/l) | LC | blood |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Chemical Formula:C6H13NO2
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SMILES:CC(C)CC(C(=O)O)N
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InChI:InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)
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InChI Key:ROHFNLRQFUQHCH-UHFFFAOYSA-N
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CAS number:328-39-2
Related resources
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Literature sources:
- Pitkänen HT et al., Serum amino acid concentrations in aging men and women., Amino acids, 413-21, 2003
- Chaleckis R et al., Individual variability in human blood metabolites identifies age-related differences., Proceedings of the National Academy of Sciences of the United States of America, 4252-9, 2016
- Lawton KA et al., Analysis of the adult human plasma metabolome., Pharmacogenomics, 383-97, 2008
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External links:
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Tissue
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Metabolite source:Homo sapiens, exogenous metabolite