LPC 18:1

Info Variations

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Name: LPC 18:1
Description: A lysophosphatidylcholine in which the remaining acyl group (position not specified) contains 18 carbons with 1 double bond. This metabolite showed statistically significant age-differences in meta... bolite levels between elderly and centenarians in both genders. (PMID: 24457528; CHEBI:64566)

Age group comparisons
PMID	Age/Age interval, Gender	Value (unit of measurement)	Method	Sample
24457528	Age 100.7 ± 2.2, Gender ⚥	24.2 (mean of regulated metabolites)	shot gun lipidomics approach	serum
24457528	Age 71 ± 6, Gender ⚥	16.8 (mean of regulated metabolites)	shot gun lipidomics approach	serum
24457528	Age 100.7 ± 2.3, Gender ♀	22.9 (mean of regulated metabolites)	shot gun lipidomics approach	serum
24457528	Age 72 ± 6, Gender ♀	18.1 (mean of regulated metabolites)	shot gun lipidomics approach	serum
24457528	Age 100.7 ± 2.3, Gender ♂	27.3 (mean of regulated metabolites)	shot gun lipidomics approach	serum
24457528	Age 72 ± 6, Gender ♂	18.1 (mean of regulated metabolites)	shot gun lipidomics approach	serum

Linear regression
PMID	Age/Age interval, Gender	Value (unit of measurement)	Method	Sample

log2 ratio/log2(FC)
PMID	Age/Age interval, Gender	Value (unit of measurement)	Method	Sample

Synonym:

lysophosphatidylcholine 18:1; LysoPC(18:1);18:1 Lyso PC
Chemical Formula:

C26H53NO8P+
Systematic name:

2-[[(2R)-2-hydroperoxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
SMILES:

CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCC[N+](C)(C)C)OO
InChI:

InChI=1S/C26H52NO8P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26(28)32-23-25(35-29)24-34-36(30,31)33-22-21-27(2,3)4/h12-13,25H,5-11,14-24H2,1-4H3,(H-,29,30,31)/p+1/b13-12-/t25-/m1/s1
InChI Key:

FXSFXPRYFCPXJV-PTGWMXDISA-O

Metabolite location:

Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Tissue
Metabolite source:

Homo sapiens, endogenous metabolite

Age group comparisons

Method: shot gun lipidomics approach

Sample: serum

PMID: 24457528