PC 16:0/18:2

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  • Name: PC 16:0/18:2
  • Description: A phosphatidylcholine 34:2 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl) and 9Z,12Z-octadecadienoyl (linoleoyl) respectively.T his metabolite showed statistically sign... ificant age-differences in metabolite levels between elderly and centenarians in both genders. (PMID: 24457528, CHEBI:73002)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
24457528 Age 100.7 ± 2.4, Gender ⚥ 599.0 (mean of regulated metabolites) shot gun lipidomics approach serum
24457528 Age 73 ± 6, Gender ⚥ 392.0 (mean of regulated metabolites) shot gun lipidomics approach serum
24457528 Age 100.7 ± 2.5, Gender ♀ 557.0 (mean of regulated metabolites) shot gun lipidomics approach serum
24457528 Age 74 ± 6, Gender ♀ 442.0 (mean of regulated metabolites) shot gun lipidomics approach serum
24457528 Age 100.7 ± 2.4, Gender ♂ 625.5 (mean of regulated metabolites) shot gun lipidomics approach serum
24457528 Age 73 ± 6, Gender ♂ 370.6 (mean of regulated metabolites) shot gun lipidomics approach serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    1-palmitoyl-2-linoleoyl-sn-glycero-3-PC; GPC(16:0/18:2); phosphatidylcholine(16:0/18:2); PLPC;16:0-18:2 PC;1-palmitoyl-2-linoleoyl-GPC; GPCho(16:0/18:2); 1-palmitoyl-2-linoleoyl-GPC (16:0/18:2)
  • Chemical Formula:
    C42H81NO8P+
  • Systematic name:
    2-[[(2R)-3-hexadecanoyloxy-2-octadeca-9,12-dienoyloxypropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
  • SMILES:
    CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCC=CCCCCC
  • InChI:
    InChI=1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/p+1/t40-/m1/s1
  • InChI Key:
    JLPULHDHAOZNQI-RRHRGVEJSA-O
  • CAS number:
    17708-90-6
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Extracellular, Human body biofluids, Biofluid tissues, Blood, Serum, Saliva, Urine, Tissue, All tissues, Cellular (general class), Subcellular, Cell membrane, Excreta material, Feces
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: shot gun lipidomics approach
Sample: serum
PubMed PMID: 24457528