PC 18:0/22:5

view
  • Name: PC 18:0/22:5
  • Description: A 1,2-diacyl-sn-glycero-3-phosphocholine in which one acyl group has 18 carbons and is fully saturated while the other has 22 carbons and 5 double bonds. This metabolite showed statistically signif... icant age-differences in metabolite levels between elderly and centenarians in both genders. (PMID: 24457528;CHEBI:90462)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
24457528 Age 100.7 ± 2.1, Gender ⚥ 12.3 (mean of regulated metabolites) shot gun lipidomics approach serum
24457528 Age 70 ± 6, Gender ⚥ 2.26 (mean of regulated metabolites) shot gun lipidomics approach serum
24457528 Age 100.7 ± 2.1, Gender ♀ 11.4 (mean of regulated metabolites) shot gun lipidomics approach serum
24457528 Age 70 ± 6, Gender ♀ 3.63 (mean of regulated metabolites) shot gun lipidomics approach serum
24457528 Age 100.7 ± 2.1, Gender ♂ 12.0 (mean of regulated metabolites) shot gun lipidomics approach serum
24457528 Age 70 ± 6, Gender ♂ 2.31 (mean of regulated metabolites) shot gun lipidomics approach serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    phosphatidylcholine (18:0/22:5); 1-stearoyl-2-docosapentaenoyl-GPC
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: shot gun lipidomics approach
Sample: serum
PubMed PMID: 24457528
Search the database by metabolite name or synonym