PC-O 28:0

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Name: PC-O 28:0
Description: An alkyl,acyl-sn-glycero-3-phosphocholine in which the alkyl or acyl groups at positions 1 and 2 contain a total of 28 carbons and no double bonds. This metabolite showed statistically significant ... age-differences in metabolite levels between elderly and centenarians in both genders. (PMID: 24457528, CHEBI:132584)

Age group comparisons
PMID	Age/Age interval, Gender	Value (unit of measurement)	Method	Sample
24457528	Age 100.7 ± 2.1, Gender ⚥	19.5 (mean of regulated metabolites)	shot gun lipidomics approach	serum
24457528	Age 70 ± 6, Gender ⚥	47.6 (mean of regulated metabolites)	shot gun lipidomics approach	serum
24457528	Age 100.7 ± 2.1, Gender ♀	21.7 (mean of regulated metabolites)	shot gun lipidomics approach	serum
24457528	Age 70 ± 6, Gender ♀	44.8 (mean of regulated metabolites)	shot gun lipidomics approach	serum
24457528	Age 100.7 ± 2.1, Gender ♂	19.5 (mean of regulated metabolites)	shot gun lipidomics approach	serum
24457528	Age 70 ± 6, Gender ♂	45.6 (mean of regulated metabolites)	shot gun lipidomics approach	serum

Linear regression
PMID	Age/Age interval, Gender	Value (unit of measurement)	Method	Sample

log2 ratio/log2(FC)
PMID	Age/Age interval, Gender	Value (unit of measurement)	Method	Sample

Synonym:

GPCho(O-28:0);phosphatidylcholine O-28:0; PC(O-28:0)
Chemical Formula:

C36H74NO7P
Systematic name:

[(2R)-2-dodecanoyloxy-3-hexadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
SMILES:

CCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCC
InChI:

InChI=1S/C36H74NO7P/c1-6-8-10-12-14-16-17-18-19-20-22-24-26-28-31-41-33-35(34-43-45(39,40)42-32-30-37(3,4)5)44-36(38)29-27-25-23-21-15-13-11-9-7-2/h35H,6-34H2,1-5H3/t35-/m1/s1
InChI Key:

KHBYFGSOHHSLQJ-PGUFJCEWSA-N

Metabolite location:

Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Tissue
Metabolite source:

Homo sapiens, endogenous metabolite

Age group comparisons

Method: shot gun lipidomics approach

Sample: serum

PMID: 24457528