pregnanediol-3-glucuronide
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Name: pregnanediol-3-glucuronide
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Description: Pregnanediol-3-glucuronide is a natural human metabolite of Pregnanediol generated in the liver by UDP glucuonyltransferase. Glucuronidation is used to assist in the excretion of toxic substances, ...
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 27374292 | Age [25-35], Gender ♀ | 4.644733 (average level of metabolite) | LC/MS negative mode | serum |
| 27374292 | Age [55-65], Gender ♀ | 0.713187 (average level of metabolite) | LC/MS negative mode | serum |
| 27374292 | Age [25-35], Gender ♂ | 1.35764 (average level of metabolite) | LC/MS negative mode | serum |
| 27374292 | Age [55-64], Gender ♂ | 0.68158 (average level of metabolite) | LC/MS negative mode | serum |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Synonym:pregnanediol-3 alpha-glucuornide;5beta-pregnane-3alpha,2-alpha-diol-3alpha-glucuronide
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Chemical Formula:C27H44O8
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Exact Mass g/mol:496.0000000
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Systematic name:(2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[[(3R,5R,8R,9S,10S,13S,14S,17S)-17-[(1S)-1-hydroxyethyl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-2-carboxylic acid
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SMILES:CC(C1CCC2C1(CCC3C2CCC4C3(CCC(C4)OC5C(C(C(C(O5)C(=O)O)O)O)O)C)C)O
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InChI:InChI=1S/C27H44O8/c1-13(28)17-6-7-18-16-5-4-14-12-15(8-10-26(14,2)19(16)9-11-27(17,18)3)34-25-22(31)20(29)21(30)23(35-25)24(32)33/h13-23,25,28-31H,4-12H2,1-3H3,(H,32,33)/t13-,14+,15+,16-,17+,18-,19-,20-,21-,22+,23-,25+,26-,27+/m0/s1
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InChI Key:ZFFFJLDTCLJDHL-JQYCEVDMSA-N
Related resources
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Literature sources:
- Saito K et al., Gender- and Age-Associated Differences in Serum Metabolite Profiles among Japanese Populations., Biological & pharmaceutical bulletin, 1179-86, 2016
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External links:
Metabolite sources and localization
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Metabolite source:Homo sapiens, endogenous metabolite