decenoylcarnitine

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  • Name: decenoylcarnitine
  • Description: Decanoylcarnitine is a member of the class of compounds known as acylcarnitines. Acylcarnitines are organic compounds containing a fatty acid with the carboxylic acid attached to carnitine through ... an ester bond. Thus, decanoylcarnitine is considered to be a fatty ester lipid molecule. Decanoylcarnitine is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Decanoylcarnitine can be found in blood, feces, and urine. Within the cell, decanoylcarnitine is primarily located in the membrane. It can also be found in the extracellular space. Acylcarnitines are useful in the diagnosis of genetic disorders such as fatty acid oxidation disorders and differentiation between biochemical phenotypes of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency disorders (PMID: 12385891 ). Moreover, decanoylcarnitine is found to be associated with very long chain acyl-CoA dehydrogenase (VLAD) deficiency, glutaric aciduria II, and celiac disease, which are inborn errors of metabolism. (HMDB0000651)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
22834969 Age 54.1 ± 13.1, Gender ♀ 79.67 (β) FIA-MS/MS serum
22834969 Age 57.7 ± 10.6, Gender ♀ 24.15 (β) FIA-MS/MS serum
22834969 Age 53.6 ± 12.5, Gender ♂ 53.66 (β) FIA-MS/MS serum
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    C10:1
  • Chemical Formula:
    C17H33NO4
  • Exact Mass g/mol:
    315.2410000
  • Systematic name:
    3-decanoyloxy-4-(trimethylazaniumyl)butanoate
  • SMILES:
    CCCCCCCCCC(=O)OC(CC(=O)[O-])C[N+](C)(C)C
  • InChI:
    InChI=1S/C17H33NO4/c1-5-6-7-8-9-10-11-12-17(21)22-15(13-16(19)20)14-18(2,3)4/h15H,5-14H2,1-4H3
  • InChI Key:
    LZOSYCMHQXPBFU-UHFFFAOYSA-N
  • CAS number:
    1492-27-9
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Urine, Tissue, Excreta material, Feces
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Linear regression
Method: FIA-MS/MS
Sample: serum
PubMed PMID: 22834969
β = 79.67 (y = βx + α)
p-value < 0.05
Linear regression
Method: FIA-MS/MS
Sample: serum
PubMed PMID: 22834969
β = 24.15 (y = βx + α)
p-value < 0.05
Linear regression
Method: FIA-MS/MS
Sample: serum
PubMed PMID: 22834969
β = 53.66 (y = βx + α)
p-value < 0.05
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