SM 24:0
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Name: SM 24:0
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Description: A sphingomyelin d18:1 in which the ceramide N-acyl group is specified as lignoceroyl (tetracosanoyl). SM 24:0 showed aging-depedent variations in human serum (CHEBI:83360).
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 23483888 | Age 30 ± 5 , Gender ⚥ | 23.4 (μM/l) | LC-MS/MS | serum |
| 23483888 | Age 70.7 ± 6, Gender ⚥ | 25.6 (μM/l) | LC-MS/MS | serum |
| 23483888 | Age 100.9 ± 2, Gender ⚥ | 19.8 (μM/l) | LC-MS/MS | serum |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Synonym:C24 sphingomyelin; SM(d18:1/24:0)
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Chemical Formula:C47H95N2O6P
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Systematic name:[(E,2S,3R)-3-hydroxy-2-(tetracosanoylamino)octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate
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SMILES:CCCCCCCCCCCCCCCCCCCCCCCC(=O)NC(COP(=O)([O-])OCC[N+](C)(C)C)C(C=CCCCCCCCCCCCCC)O
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InChI:InChI=1S/C47H95N2O6P/c1-6-8-10-12-14-16-18-20-21-22-23-24-25-26-27-29-31-33-35-37-39-41-47(51)48-45(44-55-56(52,53)54-43-42-49(3,4)5)46(50)40-38-36-34-32-30-28-19-17-15-13-11-9-7-2/h38,40,45-46,50H,6-37,39,41-44H2,1-5H3,(H-,48,51,52,53)/b40-38+/t45-,46+/m0/s1
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InChI Key:QEDPUVGSSDPBMD-XTAIVQBESA-N
Related resources
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Literature sources:
- Collino S et al., Metabolic signatures of extreme longevity in northern Italian centenarians reveal a complex remodeling of lipids, amino acids, and gut microbiota metabolism., PloS one, e56564, 2013
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External links:
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Tissue
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Metabolite source:Homo sapiens, endogenous metabolite