mandelic acid

view
  • Name: mandelic acid
  • Description: It is an isomer of cresotinic acid (2-hydroxy-3-methylbenzoic acid) and oxymethylbenzoic acid (2-methoxybenzoic acid). Derivatives of mandelic acid are formed as a result of metabolism of adrenalin... e and noradrenaline by monoamine oxidase and catechol-o-methyl transferase. It is also present in certain skin care products, is an intermediate molecule in the production of other biochemicals, may be used as an analytical reagent and is a precursor in the manufacture of dyes. Mandelic acid is an aromatic alpha hydroxy acid with the molecular formula C8H8O3. It is a white crystalline solid that is soluble in water and most common organic solvents. Mandelic acid is found to be associated with phenylketonuria, which is an inborn error of metabolism. (HMDB0000703)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
26282484 Age [20-80+], Gender ⚥ 0.0015 (β) UPLC-ESI/MSMS urine
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Chemical Formula:
    C8H8O3
  • Systematic name:
    2-hydroxy-2-phenylacetic acid
  • SMILES:
    C1=CC=C(C=C1)C(C(=O)O)O
  • InChI:
    InChI=1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)
  • InChI Key:
    IWYDHOAUDWTVEP-UHFFFAOYSA-N
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Urine, Excreta material, Feces
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Linear regression
Method: UPLC-ESI/MSMS
Sample: urine
PubMed PMID: 26282484
β = 0.0015 (y = βx + α)
p-value < 0.05
Search the database by metabolite name or synonym