dimethyl-guanosine
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Name: dimethyl-guanosine
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Description: N2,N2-Dimethylguanosine is an urinary nucleoside, a primary degradation product of tRNA. The mean levels of urinary N2,N2-Dimethylguanosine in the patients with colorectal cancer are significantly ...
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 27036001 | Age 29 ± 4, Gender ⚥ | 0.36 (CV (CV=SD of metabolite abundance (peak areas from LC-MS) divided by the mean)) | LC/MS | blood |
| 27036001 | Age 81 ± 7, Gender ⚥ | 0.76 (CV (CV=SD of metabolite abundance (peak areas from LC-MS) divided by the mean)) | LC/MS | blood |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Synonym:2-dimethylamino-6-oxypurine riboside; m22g;2,2-dimethylguanosine; N2-dimethylguanosine; 2-(dimethylamino)-9-(beta-D-ribofuranosyl)-1,9-dihydro-6H-purin-6-one; 2-(dimethylamino)-9-(β-D-ribofuranosyl)-1,9-dihydro-6H-purin-6-one; N(2),N(2)-dimethylguanosine
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Chemical Formula:C12H17N5O5
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Systematic name:9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-(dimethylamino)-6,9-dihydro-3H-purin-6-one
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SMILES:CN(C)C1=NC(=O)C2=C(N1)N(C=N2)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
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InChI:InChI=1S/C12H17N5O5/c1-16(2)12-14-9-6(10(21)15-12)13-4-17(9)11-8(20)7(19)5(3-18)22-11/h4-5,7-8,11,18-20H,3H2,1-2H3,(H,14,15,21)/t5-,7-,8-,11-/m1/s1
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InChI Key:RSPURTUNRHNVGF-IOSLPCCCSA-N
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CAS number:2140-67-2
Related resources
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Literature sources:
- Chaleckis R et al., Individual variability in human blood metabolites identifies age-related differences., Proceedings of the National Academy of Sciences of the United States of America, 4252-9, 2016
- Saito K et al., Gender- and Age-Associated Differences in Serum Metabolite Profiles among Japanese Populations., Biological & pharmaceutical bulletin, 1179-86, 2016
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External links:
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Urine, Tissue, Excreta material
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Metabolite source:Homo sapiens, endogenous metabolite