hippurate

Info Variations

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Name: hippurate
Description: An N-acylglycinate obtained by deprotonation of the carboxy group of hippuric acid (N-benzoylglycine) and its derivatives. Hippurate, the glycine conjugate of benzoic acid, is a normal constituent ... of the endogenous urinary metabolite profile and has long been associated with the microbial degradation of certain dietary components, hepatic function and toluene exposure, and is also commonly used as a measure of renal clearance. (CHEBI:132966, J. Proteome Res. 2013, 12, 4, 1527-1546)

Age group comparisons
PMID	Age/Age interval, Gender	Value (unit of measurement)	Method	Sample
18384253	Age 24.5 ± 3, Gender ⚥	0.81 (mean value of the compound area)	LC-MS; GC-MS	plasma
18384253	Age 40.8 ± 5.6, Gender ⚥	1.14 (mean value of the compound area)	LC-MS; GC-MS	plasma
18384253	Age 55.6 ± 3.7, Gender ⚥	1.23 (mean value of the compound area)	LC-MS; GC-MS	plasma
17474139	Age 36.6 ± 5.5, Gender ⚥	174.7 (mmol/mol )	H-NMR	urine
17474139	Age 54.5 ± 7.6, Gender ⚥	213.6 (mmol/mol )	H-NMR	urine
23701591	Age [35-86], Gender ⚥ (American population)	1.4 (mM)	HNMR	urine
23701591	Age [54-91], Gender ⚥ (Taiwanese population)	2.15 (mM)	HNMR	urine

Linear regression
PMID	Age/Age interval, Gender	Value (unit of measurement)	Method	Sample

log2 ratio/log2(FC)
PMID	Age/Age interval, Gender	Value (unit of measurement)	Method	Sample

Synonym:

N-benzoylglycine anions;N-benzoylglycine anion; N-benzoylglycinate; N-benzoylglycinates
Chemical Formula:

C9H8NO3-
Exact Mass g/mol:

178.0000000
Systematic name:

2-benzamidoacetate
SMILES:

C1=CC=C(C=C1)C(=O)NCC(=O)[O-]
InChI:

InChI=1S/C9H9NO3/c11-8(12)6-10-9(13)7-4-2-1-3-5-7/h1-5H,6H2,(H,10,13)(H,11,12)/p-1
InChI Key:

QIAFMBKCNZACKA-UHFFFAOYSA-M

Metabolite location:

Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Tissue
Metabolite source:

Homo sapiens, endogenous metabolite

Age group comparisons

Method: LC-MS; GC-MS

Sample: plasma

PMID: 18384253

Age group comparisons

Method: H-NMR

Sample: urine

PMID: 17474139

Age group comparisons

Method: HNMR

Sample: urine

PMID: 23701591