thyroxine

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  • Name: thyroxine
  • Description: An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions. (CHEBI:30660)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
18384253 Age 24.5 ± 3, Gender ⚥ 1.07 (mean value of the compound area) LC-MS; GC-MS plasma
18384253 Age 40.8 ± 5.6, Gender ⚥ 0.88 (mean value of the compound area) LC-MS; GC-MS plasma
18384253 Age 55.6 ± 3.7, Gender ⚥ 0.96 (mean value of the compound area) LC-MS; GC-MS plasma
8229522 Age [1-4] days, Gender ⚥ 48.1 (pmol/l) direct equilibrum dialysis serum
8229522 Age [2-20] weeks, Gender ⚥ 20.3 (pmol/l) direct equilibrum dialysis serum
8229522 Age [5-24] months, Gender ⚥ 17.0 (pmol/l) direct equilibrum dialysis serum
8229522 Age [2-7], Gender ⚥ 19.9 (pmol/l) direct equilibrum dialysis serum
8229522 Age [8-20], Gender ⚥ 17.0 (pmol/l) direct equilibrum dialysis serum
8229522 Age [21-45], Gender ⚥ 21.2 (pmol/l) direct equilibrum dialysis serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    Thx
  • Chemical Formula:
    C15H11I4NO4
  • Exact Mass g/mol:
    776.6870000
  • Systematic name:
    2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
  • SMILES:
    C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)O)N
  • InChI:
    InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)
  • InChI Key:
    XUIIKFGFIJCVMT-UHFFFAOYSA-N
  • CAS number:
    300-30-1
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: LC-MS; GC-MS
Sample: plasma
PubMed PMID: 18384253
Age group comparisons
Method: direct equilibrum dialysis
Sample: serum
PubMed PMID: 8229522
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