aspartate

view
  • Name: aspartate
  • Description: Aspartate is the ionised or deprotonated form of aspartic acid and is a metabolite revealed in human sweat, plasma and serum. (PMID: 22194922, PMID: 23838602)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
12768504 Age 32.6 ± 4.4 , Gender ♀ 29.0 (μmol/l) LC blood
12768504 Age 48 ± 4.3, Gender ♀ 18.0 (μmol/l) LC blood
12768504 Age 74.7 ± 10, Gender ♀ 16.0 (μmol/l) LC blood
12768504 Age 33.3 ± 3.8, Gender ♂ 21.0 (μmol/l) LC blood
12768504 Age 48.4 ± 6, Gender ♂ 17.0 (μmol/l) LC blood
12768504 Age 75.9 ± 9.3, Gender ♂ 13.0 (μmol/l) LC blood
27374292 Age [25–35] (median=32), Gender ♂ (Japanese) 0.967708 (average level of metabolite) UHPLC-MS/MS Negative mode serum
27374292 Age [55–64] (median=60), Gender ♂ (Japanese) 1.197744 (average level of metabolite) UHPLC-MS/MS Negative mode serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
23838602 Age [17–85], Gender ⚥ -0.006 (β) UHPLC/MS/MS serum and plasma
23838602 Age [17–85], Gender ⚥ -1.05 (β) UHPLC/MS/MS serum and plasma
23838602 Age [17–85], Gender ⚥ -0.92 (β) UHPLC/MS/MS serum and plasma
23838602 Age [17–85], Gender ⚥ -0.81 (β) UHPLC/MS/MS serum and plasma
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Chemical Formula:
    C4H5NO4-2
  • Systematic name:
    (2S)-2-aminobutanedioate
  • SMILES:
    C(C(C(=O)[O-])N)C(=O)[O-]
  • InChI:
    InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/p-2/t2-/m0/s1
  • InChI Key:
    CKLJMWTZIZZHCS-REOHCLBHSA-L
  • CAS number:
    17090-93-6
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Serum, Sweat, Tissue, Excreta material
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: LC
Sample: blood
PubMed PMID: 12768504

Age group comparisons
Method: UHPLC-MS/MS Negative mode
Sample: serum
PubMed PMID: 27374292
Linear regression
Method: UHPLC/MS/MS
Sample: serum and plasma
PubMed PMID: 23838602
β = -0.006 (y = βx + α)
p-value < 0.05

Linear regression
Method: UHPLC/MS/MS
Sample: serum and plasma
PubMed PMID: 23838602
β = -1.05 (y = βx + α)
p-value < 0.05

Linear regression
Method: UHPLC/MS/MS
Sample: serum and plasma
PubMed PMID: 23838602
β = -0.92 (y = βx + α)
p-value < 0.05

Linear regression
Method: UHPLC/MS/MS
Sample: serum and plasma
PubMed PMID: 23838602
β = -0.81 (y = βx + α)
p-value < 0.05