cotinine
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Name: cotinine
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Description: Quantitatively, the most important metabolite of nicotine in most mammalian species is cotinine. In humans, about 70 to 80% of nicotine is converted to cotinine. This transformation involves two st...
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 18384253 | Age 24.5 ± 3, Gender ⚥ | 0.34 (mean value of the compound area) | LC-MS; GC-MS | plasma |
| 18384253 | Age 40.8 ± 5.6, Gender ⚥ | 0.58 (mean value of the compound area) | LC-MS; GC-MS | plasma |
| 18384253 | Age 55.6 ± 3.7, Gender ⚥ | 0.33 (mean value of the compound area) | LC-MS; GC-MS | plasma |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Chemical Formula:C10H12N2O
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Exact Mass g/mol:176.0950000
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Systematic name:1-methyl-5-pyridin-3-ylpyrrolidin-2-one
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SMILES:CN1C(CCC1=O)C2=CN=CC=C2
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InChI:InChI=1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3
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InChI Key:UIKROCXWUNQSPJ-UHFFFAOYSA-N
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CAS number:15569-85-4
Related resources
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Literature sources:
- Lawton KA et al., Analysis of the adult human plasma metabolome., Pharmacogenomics, 383-97, 2008
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External links:
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Blood cells, Platelet, Plasma, Cerebrospinal fluid, Saliva, Urine, Organ, Brain, Gland, Gonad, Testicle, Kidney, Liver, Placenta, Tissue, Adipose tissue, Cellular (general class), Subcellular, Cytoplasm, Excreta material
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Metabolite source:Homo sapiens, exogenous metabolite