3-methylhistidine

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  • Name: 3-methylhistidine
  • Description: 3-Methylhistidine is a product of peptide bond synthesis and methylation of actin and myosin. The measurement of 3-methylhistidine provides an index of the rate of muscle protein breakdown. 3-Methy... lhistidine is a biomarker for meat consumption, especially chicken. It is also a biomarker for the consumption of soy products. The author does not specifies the stereoisomerism form of the metabolite.
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
23838602 Age [17–85], Gender ⚥ 0.008 (β) UHPLC/MS/MS serum + plasma
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    3-methyl-DL-histidine; 2-amino-3-(1-methyl-1H-imidazol-5-yl)propanoic acid
  • Chemical Formula:
    C7H11N3O2
  • Exact Mass g/mol:
    169.0851300
  • Systematic name:
    DL-Histidine, 3-methyl-
  • SMILES:
    Cn1cncc1CC(N)C(O)=O
  • InChI:
    InChI=1S/C7H11N3O2/c1-10-4-9-3-5(10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)
  • InChI Key:
    JDHILDINMRGULE-UHFFFAOYSA-N
  • CAS number:
    368-16-1
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Linear regression
Method: UHPLC/MS/MS
Sample: serum + plasma
PubMed PMID: 23838602
β = 0.008 (y = βx + α)
p-value < 0.05
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