kynurenine

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  • Name: kynurenine
  • Description: Kynurenine is a ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group. It has a role as a human metabolite. It is a substituted aniline, an aromatic k... etone and a non-proteinogenic alpha-amino acid. It is a conjugate acid of a kynureninate (Chebi:28683). The author does not specifies the stereoisomerism form of the metabolite (23-March, 2019, MC).
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
23838602 Age [17–85], Gender ⚥ 0.018 (β) UHPLC/MS/MS serum + plasma
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    dl-kynurenine; ; alanine, 3-anthraniloyl-, DL-; 3-anthraniloylalanine; alanine, 3-anthraniloyl-; 3-anthraniloyl-DL-alanine
  • Chemical Formula:
    C10H12N2O3
  • Exact Mass g/mol:
    208.0847900
  • Systematic name:
    2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
  • SMILES:
    NC(CC(=O)c1ccccc1N)C(O)=O
  • InChI:
    InChI=1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)
  • InChI Key:
    YGPSJZOEDVAXAB-UHFFFAOYSA-N
  • CAS number:
    343-65-7
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Serum, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Linear regression
Method: UHPLC/MS/MS
Sample: serum + plasma
PubMed PMID: 23838602
β = 0.018 (y = βx + α)
p-value < 0.05
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