dehydroepiandrosterone

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  • Name: dehydroepiandrosterone
  • Description: Dehydroepiandrosterone is an androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produc... ed by the adrenal glands. It has a role as an androgen, a human metabolite and a mouse metabolite. It is a 17-oxo steroid, an androstanoid and a 3beta-hydroxy-Delta(5)-steroid (CHEBI ID: 28689)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
16091484 Age [23-29], Gender ♂ 19.5 (nmol/liter) enzyme assay serum
16091484 Age [52-66], Gender ♂ 10.6 (nmol/liter) enzyme assay serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    DHEA; prasterone
  • Chemical Formula:
    C19H28O2
  • Exact Mass g/mol:
    288.0000000
  • Systematic name:
    (3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
  • SMILES:
    CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C
  • InChI:
    InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1
  • InChI Key:
    FMGSKLZLMKYGDP-USOAJAOKSA-N
Related resources
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Cerebrospinal fluid, Saliva, Urine, Tissue, Excreta material
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: enzyme assay
Sample: serum
PubMed PMID: 16091484