homovanillate (HVA)

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  • Name: homovanillate (HVA)
  • Description: Homovanillate is a hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxyl group of homovanillic acid. It has a role as a human metabolite and a mouse metabolite. It is... a conjugate base of a homovanillic acid. (CHEBI:133744)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
27374292 Age [25–35] (median=32), Gender ♀ (Japanese) 0.900384 (average level of metabolite) UHPLC-MS/MS Negative mode serum
27374292 Age [55–65] (median=60), Gender ♀ (Japanese) 1.242581 (average level of metabolite) UHPLC-MS/MS Negative mode serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    (4-hydroxy-3-methoxyphenyl)acetate; 2-(4-hydroxy-3-methoxyphenyl)ethanoate; 3-methoxy-4-hydroxyphenylacetate
  • Chemical Formula:
    C9H9O4-
  • Systematic name:
    2-(4-hydroxy-3-methoxyphenyl)acetate
  • SMILES:
    COC1=C(C=CC(=C1)CC(=O)[O-])O
  • InChI:
    InChI=1S/C9H10O4/c1-13-8-4-6(5-9(11)12)2-3-7(8)10/h2-4,10H,5H2,1H3,(H,11,12)/p-1
  • InChI Key:
    QRMZSPFSDQBLIX-UHFFFAOYSA-M
Related resources
Pathway info P = product of S = substrate of
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: UHPLC-MS/MS Negative mode
Sample: serum
PubMed PMID: 27374292