4-methyl-2-oxopentanoate

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  • Name: 4-methyl-2-oxopentanoate
  • Description: A 2-oxo monocarboxylic acid anion that is the conjugate base of 4-methyl-2-oxopentanoic acid. It has a role as a human metabolite and a Saccharomyces cerevisiae metabolite. (CHEBI:17865)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
27374292 Age [25–35] (median=32), Gender ♀ (Japanese) 1.001913 (average level of metabolite) UHPLC-MS/MS Negative mode serum
27374292 Age [55–65] (median=60), Gender ♀ (Japanese) 0.829692 (average level of metabolite) UHPLC-MS/MS Negative mode serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
23838602 Age [17–85], Gender ⚥ -0.006 (β) UHPLC/MS/MS serum + plasma
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    4-methyl-2-oxovalerate;2-oxoisocaproate; 2-keto-4-methylvalerate; α-ketoisocaproate; alpha-ketoisocaproate
  • Chemical Formula:
    C6H9O3-
  • Exact Mass g/mol:
    129.0550000
  • Systematic name:
    4-methyl-2-oxopentanoate
  • SMILES:
    CC(C)CC(=O)C(=O)[O-]
  • InChI:
    InChI=1S/C6H10O3/c1-4(2)3-5(7)6(8)9/h4H,3H2,1-2H3,(H,8,9)/p-1
  • InChI Key:
    BKAJNAXTPSGJCU-UHFFFAOYSA-M
Related resources
Pathway info P = product of S = substrate of
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Serum, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: UHPLC-MS/MS Negative mode
Sample: serum
PubMed PMID: 27374292
Linear regression
Method: UHPLC/MS/MS
Sample: serum + plasma
PubMed PMID: 23838602
β = -0.006 (y = βx + α)
p-value < 0.05