4-acetamidobutanoate

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  • Name: 4-acetamidobutanoate
  • Description: 4-acetamidobutanoate is a monocarboxylic acid anion that is the conjugate base of 4-acetamidobutanoic acid, arising from deprotonation of the carboxy group. It has a role as a human metabolite. It ... derives from a butyrate. It is a conjugate base of a 4-acetamidobutanoic acid (Chebi:11951).
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
27374292 Age [25–35] (median=32), Gender ♀ (Japanese) 0.848768 (average level of metabolite) UHPLC-MS/MS Positive mode serum
27374292 Age [55–65] (median=60), Gender ♀ (Japanese) 1.071015 (average level of metabolite) UHPLC-MS/MS Positive mode serum
27374292 Age [25–35] (median=32), Gender ♂ (Japanese) 0.952045 (average level of metabolite) UHPLC-MS/MS Positive mode serum
27374292 Age [55–64] (median=60), Gender ♂ (Japanese) 1.140449 (average level of metabolite) UHPLC-MS/MS Positive mode serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
23838602 Age [17–85], Gender ⚥ 0.015 (β) UHPLC/MS/MS serum + plasma
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    N-acetyl-4-aminobutanoate; N-acetyl-γ-aminobutyrate; N4-acetylaminobutanoate; N-acetyl-gamma-aminobutyrate;4-acetamidobutanoate; N-acetyl-4-aminobutyrate; N-acetyl-gamma-aminobutanoate;N-acetyl-4-aminobutyrate
  • Chemical Formula:
    C6H10NO3-
  • Exact Mass g/mol:
    144.0666200
  • Systematic name:
    4-acetamidobutanoate
  • SMILES:
    CC(=O)NCCCC(=O)[O-]
  • InChI:
    InChI=1S/C6H11NO3/c1-5(8)7-4-2-3-6(9)10/h2-4H2,1H3,(H,7,8)(H,9,10)/p-1
  • InChI Key:
    UZTFMUBKZQVKLK-UHFFFAOYSA-M
Related resources
Pathway info P = product of S = substrate of
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Serum, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: UHPLC-MS/MS Positive mode
Sample: serum
PubMed PMID: 27374292
Linear regression
Method: UHPLC/MS/MS
Sample: serum + plasma
PubMed PMID: 23838602
β = 0.015 (y = βx + α)
p-value < 0.05