N-acetylneuraminate

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  • Name: N-acetylneuraminate
  • Description: Sialic acids are an important family of related 9-carbon sugars acids, present on the surface of many different cells and functioning in a wide range of different biological processes.N-acetylneura... minate, the most ubiquitous species amongst the sialic acids, is widely distributed in the animal kingdom as a component of oligosaccharides, glycoproteins, and glycolipids. N-acetylneuraminate carries out various biological functions by acting as receptors for microorganisms, viruses, toxins, and hormones, by masking receptors, and by regulation of the immune system. (MetaCyc ID:N-acetylneuraminate)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
27374292 Age [25–35] (median=32), Gender ♀ (Japanese) 0.794798 (average level of metabolite) UHPLC-MS/MS HILIC serum
27374292 Age [55–65] (median=60), Gender ♀ (Japanese) 1.048926 (average level of metabolite) UHPLC-MS/MS HILIC serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    sialate;(4S,5R,6R)-5-acetylamino-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylat; Neu5Ac; (4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydropyran-2-carboxylate
  • Chemical Formula:
    C11H18NO9-
  • Systematic name:
    (4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate
  • SMILES:
    CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)[O-])O)O
  • InChI:
    InChI=1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/p-1/t5-,6+,7+,8+,9+,11?/m0/s1
  • InChI Key:
    SQVRNKJHWKZAKO-LUWBGTNYSA-M
Related resources
Pathway info P = product of S = substrate of
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: UHPLC-MS/MS HILIC
Sample: serum
PubMed PMID: 27374292