vanillylmandelate (VMA)
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Name: vanillylmandelate (VMA)
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Description: Vanillylmandelate is a hydroxy monocarboxylic acid anion that is the conjugate base of vanillylmandelic acid. It has a role as a human metabolite. It derives from a mandelate. (CHEBI:27622)
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 27374292 | Age [25–35] (median=32), Gender ♀ (Japanese) | 0.808578 (average level of metabolite) | UHPLC-MS/MS Negative mode | serum |
| 27374292 | Age [55–65] (median=60), Gender ♀ (Japanese) | 1.259252 (average level of metabolite) | UHPLC-MS/MS Negative mode | serum |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Synonym:3-methoxy-4-hydroxymandelate; vanilmandelate; 3-methoxy-4-hydroxyphenylhydroxyacetate; 4-hydroxy-3-methoxy-DL-mandelate; 4-hydroxy-3-methoxymandelate
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Chemical Formula:C9H9O5-
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Systematic name:2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetate
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SMILES:COC1=C(C=CC(=C1)C(C(=O)[O-])O)O
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InChI:InChI=1S/C9H10O5/c1-14-7-4-5(2-3-6(7)10)8(11)9(12)13/h2-4,8,10-11H,1H3,(H,12,13)/p-1
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InChI Key:CGQCWMIAEPEHNQ-UHFFFAOYSA-M
Related resources
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Literature sources:
- Saito K et al., Gender- and Age-Associated Differences in Serum Metabolite Profiles among Japanese Populations., Biological & pharmaceutical bulletin, 1179-86, 2016
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External links:
Pathway info P = product of S = substrate of
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Tyrosine metabolism S P other metabolites from MetaboAge4-hydroxyphenylacetate Norepinephrine Vanillylmandelic acid (VMA) fumaric acid homovanillate (HVA) normetanephrine p-hydroxyphenylacetic acid pyruvate
Metabolic pathways other metabolites from MetaboAge1,7-dimethyluric acid 1-methylnicotinamide 1-methylxanthine 11,12-dihydroxy-eicosatrienoic acid 4-acetamidobutanoate 4-hydroxybenzoic acid 4-hydroxyphenylacetate 4-methyl-2-oxopentanoate D-glucose D-glucuronate D-mannitol D-mannose D-ribose D-sorbitol D-xylose Dihydroxymandelic acid (DHMA) L-citrulline L-threonine N-acetylneuraminate N-acetylornithine N-methyl-4-pyridone-3-carboxamide N6-acetyl-lysine NAD+ NADP+ Norepinephrine UDP-acetyl-glucosamine Vanillylmandelic acid (VMA) acetone acetylphenylalanine alpha-tocopherol androstenedione arachidonic acid arginine beta-hydroxyisovalerate beta-tocopherol betaine caffeine campesterol carnosine cholesterol choline choline phosphate citric acid cortisone creatine creatinine dehydroepiandrosterone dimethyl sulfone dimethylamine dimethylglycine fumaric acid gamma-tocopherol glutarate glutathione glycine guanidinoacetic acid gulonic acid homovanillate (HVA) hypoxanthine inosine inositol 1-phosphate kynurenic acid leukotriene E4 linoleic acid myo-inositol niacinamide nicotinic acid normetanephrine oxalic acid p-hydroxyphenylacetic acid paraxanthine phenylglyoxylic acid pregnelone propylene glycol pyridoxic acid pyruvate quinic acid scyllo-inositol sphingosine 1-phosphate taurine theobromine trans-4-hydroxyproline trimethylamine N-oxide tryptamine urate urea uric acid uridine xanthine
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Tissue
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Metabolite source:Homo sapiens, endogenous metabolite