N-methyl-4-pyridone-3-carboxamide
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Name: N-methyl-4-pyridone-3-carboxamide
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Description: N1-Methyl-4-pyridone-5-carboxamide (4PY ) is a normal human metabolite (one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation) (HMDB0004194)
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 23701591 | Age [34-39], Gender ⚥ (American population) | 0.22 (signal intensity) | HNMR | urine |
| 23701591 | Age [72-84], Gender ⚥ (American population) | 0.45 (signal intensity) | HNMR | urine |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Synonym:N(1)-methyl-4-pyridone-5-carboxamide; 4PY
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Chemical Formula:C7H8N2O2
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Exact Mass g/mol:152.0000000
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Systematic name:1-methyl-4-oxopyridine-3-carboxamide
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SMILES:CN1C=CC(=O)C(=C1)C(=O)N
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InChI:InChI=1S/C7H8N2O2/c1-9-3-2-6(10)5(4-9)7(8)11/h2-4H,1H3,(H2,8,11)
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InChI Key:KTLRWTOPTKGYQY-UHFFFAOYSA-N
Related resources
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Literature sources:
- Swann JR et al., Microbial-mammalian cometabolites dominate the age-associated urinary metabolic phenotype in Taiwanese and American populations., Journal of proteome research, 3166-80, 2013
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External links:
Pathway info P = product of S = substrate of
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Metabolic pathways other metabolites from MetaboAge1,7-dimethyluric acid 1-methylnicotinamide 1-methylxanthine 11,12-dihydroxy-eicosatrienoic acid 4-acetamidobutanoate 4-hydroxybenzoic acid 4-hydroxyphenylacetate 4-methyl-2-oxopentanoate D-glucose D-glucuronate D-mannitol D-mannose D-ribose D-sorbitol D-xylose Dihydroxymandelic acid (DHMA) L-citrulline L-threonine N-acetylneuraminate N-acetylornithine N6-acetyl-lysine NAD+ NADP+ Norepinephrine UDP-acetyl-glucosamine Vanillylmandelic acid (VMA) acetone acetylphenylalanine alpha-tocopherol androstenedione arachidonic acid arginine beta-hydroxyisovalerate beta-tocopherol betaine caffeine campesterol carnosine cholesterol choline choline phosphate citric acid cortisone creatine creatinine dehydroepiandrosterone dimethyl sulfone dimethylamine dimethylglycine fumaric acid gamma-tocopherol glutarate glutathione glycine guanidinoacetic acid gulonic acid homovanillate (HVA) hypoxanthine inosine inositol 1-phosphate kynurenic acid leukotriene E4 linoleic acid myo-inositol niacinamide nicotinic acid normetanephrine oxalic acid p-hydroxyphenylacetic acid paraxanthine phenylglyoxylic acid pregnelone propylene glycol pyridoxic acid pyruvate quinic acid scyllo-inositol sphingosine 1-phosphate taurine theobromine trans-4-hydroxyproline trimethylamine N-oxide tryptamine urate urea uric acid uridine vanillylmandelate (VMA) xanthine
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Urine, Tissue, Cellular (general class), Subcellular, Cytoplasm, Excreta material