pyruvate

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  • Name: pyruvate
  • Description: Pyruvate is a 2-oxo monocarboxylic acid anion that is the conjugate base of pyruvic acid, which is an important metabolic product for energy-producing biochemical pathways. Pyruvate arises from de... protonation of the carboxyl group of pyruvic acid. It has a role as a fundamental metabolite. Pyruvate is the final product of glycolysis and, when hypoxic conditions arise, can be metabolized anaerobically to form lactate. This chemical is a precursor of both acetyl-coenzyme A and oxaloacetate, which are involved in the citric acid cycle. Additionally, oxaloacetate is a substrate in the gluconeogenesis pathway. (CHEBI:15361)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
23838602 Age 53.41 ± 13.99 , Gender ⚥ 0.008 (β) UHPLC/MS/MS serum and plasma
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    pyruvate anion; α-ketopropionate; alpha-ketopropionate
  • Chemical Formula:
    C3H3O3-
  • Exact Mass g/mol:
    87.0080000
  • Systematic name:
    2-oxopropanoate
  • SMILES:
    CC(=O)C(=O)[O-]
  • InChI:
    InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)/p-1
  • InChI Key:
    LCTONWCANYUPML-UHFFFAOYSA-M
  • CAS number:
    57-60-3
Related resources
Pathway info P = product of S = substrate of
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Plasma, Serum, Tissue
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Linear regression
Method: UHPLC/MS/MS
Sample: serum and plasma
PubMed PMID: 23838602
β = 0.008 (y = βx + α)
p-value < 0.05
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