normetanephrine
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Name: normetanephrine
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Description: Normetanephrine is a methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.(HMDB0000819)
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 3972962 | Age [30-40], Gender ⚥ | 0.27 (nmol/m^2/min) | HPLC | urine |
| 3972962 | Age [63-85], Gender ⚥ | 0.43 (nmol/m^2/min) | HPLC | urine |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Synonym:3-o-methyl-noradrenaline; normetadrenaline;3-methoxy-noradrenaline
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Chemical Formula:C9H13NO3
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Exact Mass g/mol:183.0000000
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Systematic name:4-(2-amino-1-hydroxyethyl)-2-methoxyphenol
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SMILES:COC1=C(C=CC(=C1)C(CN)O)O
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InChI:InChI=1S/C9H13NO3/c1-13-9-4-6(8(12)5-10)2-3-7(9)11/h2-4,8,11-12H,5,10H2,1H3
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InChI Key:YNYAYWLBAHXHLL-UHFFFAOYSA-N
Related resources
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Literature sources:
- Hoeldtke RD, Cilmi KM, Effects of aging on catecholamine metabolism., The Journal of clinical endocrinology and metabolism, 479-84, 1985
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External links:
Pathway info P = product of S = substrate of
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Tyrosine metabolism S P other metabolites from MetaboAge4-hydroxyphenylacetate Norepinephrine Vanillylmandelic acid (VMA) fumaric acid homovanillate (HVA) p-hydroxyphenylacetic acid pyruvate vanillylmandelate (VMA)
Metabolic pathways other metabolites from MetaboAge1,7-dimethyluric acid 1-methylnicotinamide 1-methylxanthine 11,12-dihydroxy-eicosatrienoic acid 4-acetamidobutanoate 4-hydroxybenzoic acid 4-hydroxyphenylacetate 4-methyl-2-oxopentanoate D-glucose D-glucuronate D-mannitol D-mannose D-ribose D-sorbitol D-xylose Dihydroxymandelic acid (DHMA) L-citrulline L-threonine N-acetylneuraminate N-acetylornithine N-methyl-4-pyridone-3-carboxamide N6-acetyl-lysine NAD+ NADP+ Norepinephrine UDP-acetyl-glucosamine Vanillylmandelic acid (VMA) acetone acetylphenylalanine alpha-tocopherol androstenedione arachidonic acid arginine beta-hydroxyisovalerate beta-tocopherol betaine caffeine campesterol carnosine cholesterol choline choline phosphate citric acid cortisone creatine creatinine dehydroepiandrosterone dimethyl sulfone dimethylamine dimethylglycine fumaric acid gamma-tocopherol glutarate glutathione glycine guanidinoacetic acid gulonic acid homovanillate (HVA) hypoxanthine inosine inositol 1-phosphate kynurenic acid leukotriene E4 linoleic acid myo-inositol niacinamide nicotinic acid oxalic acid p-hydroxyphenylacetic acid paraxanthine phenylglyoxylic acid pregnelone propylene glycol pyridoxic acid pyruvate quinic acid scyllo-inositol sphingosine 1-phosphate taurine theobromine trans-4-hydroxyproline trimethylamine N-oxide tryptamine urate urea uric acid uridine vanillylmandelate (VMA) xanthine
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Blood cells, Platelet, Cerebrospinal fluid, Urine, Organ, Brain, Gland, Adrenal gland, Tissue, Cellular (general class), Subcellular, Cytoplasm, Excreta material, Feces
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Metabolite source:Homo sapiens, endogenous metabolite