sphingosine 1-phosphate

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  • Name: sphingosine 1-phosphate
  • Description: A phosphosphingolipid that consists of sphingosine having a phospho group attached at position 1. Sphingosine-1-phosphate (S1P) is a signaling sphingolipid, also known as lysosphingolipid. It is al... so referred to as a bioactive lipid mediator. Sphingolipids at large form a class of lipids characterized by a particular aliphatic aminoalcohol, which is sphingosine. (CHEBI:37550; https://en.wikipedia.org/wiki/Sphingosine-1-phosphate)
Overview of age-variations
Age group comparisons
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
27374292 Age [25–35] (median=32), Gender ♂ 0.899498 (mean value of the compound area) LC/MS HILIC serum
27374292 Age [55-64] (median=60), Gender ♂ 1.133595 (mean value of the compound area) LC/MS HILIC serum
Linear regression
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
log2 ratio/log2(FC)
PMID Age/Age interval, Gender Value (unit of measurement) Method Sample
Summary
  • Synonym:
    S1P;C18-Sphingosine 1-phosphate;D-erythro-sphingosine 1-phosphate
  • Chemical Formula:
    C18H38NO5P
  • Systematic name:
    [(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enyl] dihydrogen phosphate
  • SMILES:
    CCCCCCCCCCCCCC=CC(C(COP(=O)(O)O)N)O
  • InChI:
    InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1
  • InChI Key:
    DUYSYHSSBDVJSM-KRWOKUGFSA-N
  • CAS number:
    26993-30-6
Related resources
Pathway info P = product of S = substrate of
Metabolite sources and localization
  • Metabolite location:
    Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Blood cells, Platelet, Serum, Tissue, Connective tissue, Connective tissue cell, Fibroblast, Cellular (general class), Subcellular, Cell membrane, Cytoplasm, Endoplasmic reticulum, Endosome
  • Metabolite source:
    Homo sapiens, endogenous metabolite
Age-variations
Age group comparisons
Method: LC/MS HILIC
Sample: serum
PubMed PMID: 27374292