niacinamide
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Name: niacinamide
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Description: An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this com...
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 27374292 | Age [25-35], Gender ♂ | 1.506537 (average level of metabolite) | LC/MS positive mode | serum |
| 27374292 | Age [55-64], Gender ♂ | 0.972584 (average level of metabolite) | LC/MS positive mode | serum |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Synonym:nicotinamide; beta-pyridinecarboxamide; pyridine-3-carboxamide; 3-pyridinecarboxamide; nicotinic acid amide
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Chemical Formula:C6H6N2O
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Exact Mass g/mol:122.0000000
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Systematic name:pyridine-3-carboxamide
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SMILES:C1=CC(=CN=C1)C(=O)N
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InChI:InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
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InChI Key:DFPAKSUCGFBDDF-UHFFFAOYSA-N
Related resources
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Literature sources:
- Saito K et al., Gender- and Age-Associated Differences in Serum Metabolite Profiles among Japanese Populations., Biological & pharmaceutical bulletin, 1179-86, 2016
Pathway info P = product of S = substrate of
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Nicotinate and nicotinamide metabolism S P other metabolites from MetaboAge1-methylnicotinamide N-methyl-4-pyridone-3-carboxamide NAD+ NADP+ fumaric acid nicotinic acid pyruvate
Metabolic pathways other metabolites from MetaboAge1,7-dimethyluric acid 1-methylnicotinamide 1-methylxanthine 11,12-dihydroxy-eicosatrienoic acid 4-acetamidobutanoate 4-hydroxybenzoic acid 4-hydroxyphenylacetate 4-methyl-2-oxopentanoate D-glucose D-glucuronate D-mannitol D-mannose D-ribose D-sorbitol D-xylose Dihydroxymandelic acid (DHMA) L-citrulline L-threonine N-acetylneuraminate N-acetylornithine N-methyl-4-pyridone-3-carboxamide N6-acetyl-lysine NAD+ NADP+ Norepinephrine UDP-acetyl-glucosamine Vanillylmandelic acid (VMA) acetone acetylphenylalanine alpha-tocopherol androstenedione arachidonic acid arginine beta-hydroxyisovalerate beta-tocopherol betaine caffeine campesterol carnosine cholesterol choline choline phosphate citric acid cortisone creatine creatinine dehydroepiandrosterone dimethyl sulfone dimethylamine dimethylglycine fumaric acid gamma-tocopherol glutarate glutathione glycine guanidinoacetic acid gulonic acid homovanillate (HVA) hypoxanthine inosine inositol 1-phosphate kynurenic acid leukotriene E4 linoleic acid myo-inositol nicotinic acid normetanephrine oxalic acid p-hydroxyphenylacetic acid paraxanthine phenylglyoxylic acid pregnelone propylene glycol pyridoxic acid pyruvate quinic acid scyllo-inositol sphingosine 1-phosphate taurine theobromine trans-4-hydroxyproline trimethylamine N-oxide tryptamine urate urea uric acid uridine vanillylmandelate (VMA) xanthine
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Extracellular, Human body biofluids, Biofluid tissues, Blood, Breast milk, Urine, Organ, Bladder, Pancreas, Placenta, Prostate, Skin, Skin tissue, Epidermis, Spleen, Tissue, Connective tissue, Connective tissue cell, Fibroblast, Nervous tissue, Nervous tissue cells, Nerve cell, Excreta material, Feces
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Metabolite source:Homo sapiens, endogenous metabolite