scyllo-inositol
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Name: scyllo-inositol
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Description: A stereoisomer of inositol and a plant sugar alcohol found most abundantly in coconut palm trees, with potential amyloid plaque formation inhibitory activity. Following oral administration, scyllit...
Overview of age-variations
| Age group comparisons | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| 15468140 | Age [24-29], Gender ⚥ | 0.3 (nM) | H-MRS | white matter |
| 15468140 | Age [46-71], Gender ⚥ | 0.43 (nM) | H-MRS | white matter |
| 23701591 | Age [34-39], Gender ⚥ (American population) | 1.0 (signal intensity) | HNMR | urine |
| 23701591 | Age [72-84], Gender ⚥ (American population) | 1.25 (signal intensity) | HNMR | urine |
| 27374292 | Age [25–35] (median=32), Gender ♀ | 0.825468 (mean value of the compound area) | GC/MS | serum |
| 27374292 | Age [55-65] (median=60), Gender ♀ | 1.294049 (mean value of the compound area) | GC/MS | serum |
| Linear regression | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
| log2 ratio/log2(FC) | ||||
|---|---|---|---|---|
| PMID | Age/Age interval, Gender | Value (unit of measurement) | Method | Sample |
Summary
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Synonym:ELND005; cocositol;scyllitol; quercinitol; AZD-103
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Chemical Formula:C6H12O6
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Systematic name:cyclohexane-1,2,3,4,5,6-hexol
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SMILES:C1(C(C(C(C(C1O)O)O)O)O)O
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InChI:InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H
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InChI Key:CDAISMWEOUEBRE-UHFFFAOYSA-N
Related resources
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Literature sources:
- Saito K et al., Gender- and Age-Associated Differences in Serum Metabolite Profiles among Japanese Populations., Biological & pharmaceutical bulletin, 1179-86, 2016
- Swann JR et al., Microbial-mammalian cometabolites dominate the age-associated urinary metabolic phenotype in Taiwanese and American populations., Journal of proteome research, 3166-80, 2013
- Kaiser LG et al., Scyllo-inositol in normal aging human brain: 1H magnetic resonance spectroscopy study at 4 Tesla., NMR in biomedicine, 51-5, 2005
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External links:
Pathway info P = product of S = substrate of
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Metabolic pathways other metabolites from MetaboAge1,7-dimethyluric acid 1-methylnicotinamide 1-methylxanthine 11,12-dihydroxy-eicosatrienoic acid 4-acetamidobutanoate 4-hydroxybenzoic acid 4-hydroxyphenylacetate 4-methyl-2-oxopentanoate D-glucose D-glucuronate D-mannitol D-mannose D-ribose D-sorbitol D-xylose Dihydroxymandelic acid (DHMA) L-citrulline L-threonine N-acetylneuraminate N-acetylornithine N-methyl-4-pyridone-3-carboxamide N6-acetyl-lysine NAD+ NADP+ Norepinephrine UDP-acetyl-glucosamine Vanillylmandelic acid (VMA) acetone acetylphenylalanine alpha-tocopherol androstenedione arachidonic acid arginine beta-hydroxyisovalerate beta-tocopherol betaine caffeine campesterol carnosine cholesterol choline choline phosphate citric acid cortisone creatine creatinine dehydroepiandrosterone dimethyl sulfone dimethylamine dimethylglycine fumaric acid gamma-tocopherol glutarate glutathione glycine guanidinoacetic acid gulonic acid homovanillate (HVA) hypoxanthine inosine inositol 1-phosphate kynurenic acid leukotriene E4 linoleic acid myo-inositol niacinamide nicotinic acid normetanephrine oxalic acid p-hydroxyphenylacetic acid paraxanthine phenylglyoxylic acid pregnelone propylene glycol pyridoxic acid pyruvate quinic acid sphingosine 1-phosphate taurine theobromine trans-4-hydroxyproline trimethylamine N-oxide tryptamine urate urea uric acid uridine vanillylmandelate (VMA) xanthine
Metabolite sources and localization
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Metabolite location:Human organism, Body part, Human body biofluids, Biofluid tissues, Blood, Serum, Cerebrospinal fluid, Saliva, Urine, Organ, Brain, Cerebral cortex, Motor cortex, White metter, Lateral ventricles, Corona radiata, Spinal cord, Tissue, Nervous tissue, Excreta material, Feces
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Metabolite source:Homo sapiens, exogenous metabolite